Rivaroxaban: Compatibilty with Pharmaceutical Excipients using DSC and FTIR Spectrophotometry
نویسندگان
چکیده
Rivaroxaban (RN) is a recently developed potent oral anticoagulant. The aim of the present study envisages compatibility studies rivaroxaban with crospovidone, sodium startch glycolate, magnesium stearate, talc, microcrystalline cellulose, aerosil, HPMC K100 M, croscarmellose using Differential scanning calorimeter and FTIR spectrophotometer. DSC thermograms, physical mixture individual pharmaceutical excipient, exhibited range transition drug in between 224ºC 232ºC. graphs showed that wave numbers rivaroxaban, matched all chosen excipients combinations. Thus RN was not interactive selected can be carried forward for further studies.
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ژورنال
عنوان ژورنال: Journal of pharmaceutical research international
سال: 2022
ISSN: ['2456-9119']
DOI: https://doi.org/10.9734/jpri/2022/v34i12a35554